TWENTY YEARS OF NEONATAL SCREENING FOR SICKLE CELL DISEASE IN BRAZIL: THE CHALLENGES OF A CONTINENTAL COUNTRY WITH HIGH GENETIC HETEROGENEITY

Twenty Years of Neonatal Screening for Sickle Cell Disease in Brazil: The Challenges of a Continental Country with High Genetic Heterogeneity

Abstract Sickle cell disease (SCD) is the most common inherited hematological disease worldwide.The benefits of diagnosis and early intervention have led to the wide dissemination of public health programs worldwide.Through neonatal screening programs, it is possible to reduce morbidity and mortality in the first 5 years of life.The prophylactic us

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Effects of public health interventions on the epidemiological spread during the first wave of the COVID-19 outbreak in Thailand.

A novel infectious respiratory disease was recognized in Wuhan (Hubei Province, China) in December 2019.In February 2020, the disease was named "coronavirus disease 2019" (COVID-19).COVID-19 became a pandemic in March 2020, and, since then, different countries have implemented a broad spectrum of policies.Thailand Pre-Packs- Eye And Ear Care is con

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Natech: Extreme Wind Likelihood Method Analysis

Industrial accidents can be triggered by natural hazards (as earthquakes, floods, lightning, and extreme temperatures) which can result in fires, explosions, or release of hazardous substances.These high impact accidents are called NaTech (Natural Hazards Triggered Technological Accident).NaTech can determine huge damages and their rapid growth in

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Effects of ovule and seed abortion on brood size and fruit costs in the leguminous shrub Caesalpinia gilliesii (Wall. ex Hook.) D. Dietr

For several plant species, brood size results from the abortion of ovules and seeds.However, these processes have rarely been studied together in wild plants.In some of the leguminous species studied, seed abortion has been found to depend on pollen quality and on the position of the ovule or fruit.The direct consequence for the mother plant is tha

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